Are these safe for an autoclave?

Yes they are. That is the primary purpose of the pouches.

Do these have indicators for when the optimal temperature is reached for sterilization?

Yes they do. PlastCare USA pouches come with larger indicators than the others on the market.

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200 5.25 x 10 Self Sealing Sterilization Pouches - Autoclave Sterilizer Bags Pouch for Sterilizing Dental Medical Instruments and Cleaning Tools - Latex-Free, Color Changin Indicator by PlastCare USA

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