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Differin Acne Spot Treatment delivers maximum strength 10% benzoyl peroxide in a fast-acting, four-in-one formula that treats, prevents, and smooths acne-prone skin. Enhanced with glycerin to reduce dryness, this targeted spot treatment visibly reduces blemish size and redness after just one use, making it the go-to solution for professionals who demand effective, no-nonsense skincare.












| ASIN | B0D355W5F2 |
| Best Sellers Rank | #3,099 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #101 in Facial Serums |
| Customer Reviews | 4.5 4.5 out of 5 stars (830) |
| Item model number | 0299.053078 |
| Manufacturer | Galderma |
| Package Dimensions | 6.42 x 2.68 x 1.65 inches; 1.76 ounces |
| UPC | 302994611003 |
J**S
Acne was inconvenienced, skin was grateful
This spot treatment and I have a very neutral, respectful relationship. It didn’t nuke my acne overnight, but it did calm things down without burning, peeling, or making my face feel like it was being punished. Super comfortable on the skin — no tightness, no drama. Also worth it for the price. A little goes a long way, and it actually works quietly in the background instead of wrecking your moisture barrier. My acne wasn’t terrified, but it was definitely humbled. Would repurchase for the value and the lack of chaos.
D**A
Great for occasional blemishes. Powerful stuff.
This product works great on facial blemishes (pimples). A little dab will do ya! Use only on the spot needed. It's too harsh and not intended for large areas or whole face application...unless your blemishes occupy a larger area than just single spots.
J**K
Healed 75% of my acne in 12hrs
This got rid of my acne in less than a day. Put this on my forehead acnes at 11am, looked in the mirror at 11pm and my acne was 75% reduced. Its amazing it can work so fast in 12hrs.
E**A
Works wonders
These patches work really well! They stay on overnight and noticeably reduce redness and size by morning. A must-have for quick spot treatment.
A**R
Works wonders
Good product
S**E
Highly effective
I think this product just goes to show that just because a product is expensive or from major brand doesn’t mean it’s the best. I have tried a gazillion products and different price points and I can confidently say this is probably the best I’ve ever had. Not only is it effective it is also very effective. I would say you need to use it for atleast 6 months. Consistency beats intensity.
S**N
Amazing spot treatment, pimple gone in two days
I used a laroche posay benzoyl peroxide cream but it got discontinued, so I was looking for a new one. This one works just the same and maybe even better. I had a pimple forming and in just two days of using this, it was gone. I would highly recommend this spot treatment
F**4
Works but not great
I’ve been using Differin for a few weeks now and it does help with acne over time, but it definitely requires patience. The first couple of weeks caused noticeable dryness, redness, and some peeling, even when using it sparingly. Once my skin adjusted, I did start to see fewer breakouts, but it’s not the miracle product some reviews make it sound like. If you’re willing to stick with it and use a good moisturizer, it can be effective—but be prepared for an adjustment period and gradual results.
S**A
I received a fake product. The tube had no seal on it. And i bought it for 100 SAR. The audacity to sell fake product in the name of orignal for an orignal price.
Trustpilot
2 months ago
2 weeks ago