E45 Dermatological Itch Relief Cream - 500g

Stops itching

HEAVEN in a bottle 🙌🏽🙌🏽🙌🏽🙌🏽 I have been suffering with eczema on both of my hands, of all places since June 2025 and I have literally tried EVERYTHING.. nothing works. Not even the prescribed medication. Long story short I read a post about E45 on Facebook about the same condition I have. Extreme itching, eczema. Yada Yada.. it hasn’t even been 24 hours. I could cry 😭 I know it’s pricey but it’s worth it!

Well I didn’t hold out much hope as nothing so far has taken away my Itching. But OMG as soon as it was applied. It felt cold which was amazing in itself. But the Itch was gone. I’m so happy. I am totally bedbound. I can’t even move by myself. So when I get an itch which I do all of the time. It’s horrible as I can’t reach it and also as my skin is so fragile. Scratching just opens it all up. I can’t sleep at night because of the itching. I can’t describe the feeling if not itching. It’s amazing. Just give it a go. What gave you got to lose. And yes it might be a tad expensive. But a little goes along way. And taking away the itching. I would have paid anything. So to me this is a small price to pay.

Bought this for my father in law bc he was itching like crazy!! I think he has excema but won't go get it checked out. He would itch until the point of bleeding. So a friend told me about this cream that helped her. I ordered it and low and behold it worked! He loves it so much the bottle is almost empty and I got it like 6 months ago. It was very effective for him and he stopped itching when he put it on. Will be buying again for him and also no more bleeding thank god!

I am a 75 year old female who has been plagued with severe rashless overall body itch for years. It has kept me awake at night and caused extreme anxiety. Up until now the only product that helped was Cerave anti-itch lotion with pramoxine. This was somewhat soothing for an hour or so but not always. An article I read on itchy skin mentioned E45. I researched the ingredients, lauromacrogols and urea, and decided to take a chance. It is a miracle. I have been using it for five days, and in that time I have experienced longer and longer periods of total relief. If I wake in the night with a burning itch, an application of E45 gives me almost immediate relief. Whereas before I had to apply lotion every 3-4 hours 24 hours a day, now I can go with two daily applications about 12 hours apart. I am not saying this will work for everyone; nothing does. But for anyone who is desperate and has tried everything else, I would say give this a shot. It's expensive, but if it relieves the torment then it is cheap.