---
product_id: 1780629
title: "API STRESS ZYME"
brand: "api"
price: "€ 33.26"
currency: EUR
in_stock: null
reviews_count: 13
category: "Api"
url: https://www.desertcart.it/products/1780629-api-stress-zyme
store_origin: IT
region: Italy
---

# Safe for freshwater & saltwater 300M+ live bacteria per tsp Consumes sludge & organic waste API STRESS ZYME

**Brand:** api
**Price:** € 33.26
**Availability:** ❌ Out of Stock

## Summary

> 🧪 Transform your tank maintenance into a stress-free ritual with nature’s own powerhouse!

## Quick Answers

- **What is this?** API STRESS ZYME by api
- **How much does it cost?** € 33.26 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.it](https://www.desertcart.it/products/1780629-api-stress-zyme)

## Best For

- api enthusiasts

## Why This Product

- Trusted api brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted Legacy:** Backed by nearly 60 years of API expertise, delivering proven, reliable results for your aquatic ecosystem.
- • **Prolongs Filter Life:** Boosts natural aquarium cycles, allowing filters to stay cleaner longer and reducing costly replacements.
- • **Effortless Weekly Use:** Simple weekly dosing maintains a strong biological filter, reducing time spent on tank upkeep.
- • **Powerful Bio-Cleaning:** Over 300 million live bacteria actively break down sludge and organic debris, keeping your tank pristine.
- • **Dual Habitat Compatibility:** Formulated for both freshwater and saltwater aquariums, ensuring versatile, all-in-one maintenance.

## Overview

API STRESS ZYME is a 16-ounce aquarium cleaning solution packed with over 300 million live bacteria per teaspoon that naturally consume sludge and organic waste. Safe for both freshwater and saltwater tanks, it supports a strong biological filter and reduces maintenance when used weekly. Trusted for nearly six decades, this solution keeps your aquarium crystal clear and healthy, extending filter life and enhancing aquatic life vitality.

## Description

Reduce aquarium maintenance by creating a naturally balanced aquarium with API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution. Fish waste, sludge, uneaten food and other organic compounds can cause harmful water conditions including ammonia and nitrite poisoning and breathing difficulty. They can also be difficult and time-consuming to remove especially from rock, coral and gravel. API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution contains over 300 million live bacteria per teaspoonful to consume sludge and organic debris, keeping gravel and glass clean naturally and boosting the natural aquarium cycle, reducing aquarium maintenance over time. Use it weekly in freshwater and saltwater aquariums to maintain a strong biological filter and a healthy, clean aquarium. With API aquarium products, it’s easy to keep a beautiful saltwater, freshwater or reef aquarium. For almost 60 years API has developed premium solutions with proven and effective results for your family and ours. API offers a range of testing kits, water conditioners, and nutritionally superior food, because we’re dedicated to making a better underwater world. They work to provide a safe, hospitable environment for fish such as tropical community fish, cichlids, goldfish and more. At API, we understand the rewards and relaxation of fishkeeping because we have a passion for fish too.

Review: Clear water - It works great. Keep my water crystal clear.
Review: Amazing product. Really works. - I use this weekly, RELIGIOUSLY. I do not miss a dose. This is my tank today, having not touched the filter in 18 months. (Fluval FX6 filled with only biohome filter media and polishing sponges.) I’ve only changed out the live plants when needed (pothos houseplant clippings) and used the magnetic algae glass scraper when needed. It’s a 75 gallon tank. I8 MONTHS!!! I highly recommend this product. Zero odor, zero nastiness.

## Features

- Contains one (1) API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution 16-Ounce Bottle
- Keeps freshwater and saltwater aquariums clean and reduces maintenance
- Consumes sludge to help keep gravel and decorations clean
- Adds beneficial bacteria for a healthy aquarium
- Use weekly to maintain a clean, healthy aquarium

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B000255N3W |
| ASIN  | B000255N3W |
| Best Sellers Rank | #3,565 in Pet Supplies ( See Top 100 in Pet Supplies ) #21 in Aquarium Water Treatments |
| Brand Name | API |
| Color | multi natural |
| Country of Origin | United States |
| Customer Reviews | 4.8 4.8 out of 5 stars (12,025) |
| Date First Available | June 20, 2004 |
| Date First Available  | June 20, 2004 |
| Department | Unisex-Adult |
| Department  | Unisex-Adult |
| Directions | Use weekly for a healthy, clean aquarium and to maintain a strong biological filter. Shake well. Using dosing cap on bottle, add 5 ml per 10 gallons (38 L) of water. For new aquariums and to help boost the biological filter, double the dose at start-up and use for 2 additional weeks. |
| Is Discontinued By Manufacturer  | Yes |
| Item Dimensions LxWxH | 10 x 10 x 10 inches |
| Item Package Dimensions L x W x H | 8.48 x 2.36 x 2.28 inches |
| Item Weight | 544.31 Grams |
| Item model number | 56E |
| Item model number  | 56E |
| Manufacturer | Mars Fishcare |
| Manufacturer  | Mars Fishcare |
| Manufacturer recommended age  | 1 month and up |
| Material | Plastic |
| Model Name | STRESS ZYME, 16 OZ |
| Number of Items | 1 |
| Product Dimensions  | 10 x 10 x 10 inches; 1.2 Pounds |
| Size | 16 oz |
| Style | Freshwater |
| Target Audience Keyword | fish |

## Product Details

- **Brand:** API
- **Item Form:** Liquid
- **Item Weight:** 544.31 Grams
- **Liquid Volume:** 473 Milliliters
- **Manufacturer:** Mars Fishcare

## Images

![API STRESS ZYME - Image 1](https://m.media-amazon.com/images/I/71NW462aaAL.jpg)

## Available Options

This product comes in different **Color, Size** options.

## Questions & Answers

**Q: Can I mix this with API Quick Start and API Stress Coat+ in a gallon every time I do water changes weekly? Or just pour it directly in my 5.5 tank?**
A: In short, you don't need the Stress Zyme if you already are using the Quick Start.  Here's a longer answer:The API Stress Coat is primarily a de-chlorinator and has aloe added to help maintain a healthy slime coat on the fish so this should always be added to the water and mixed before adding to the tank.  The API Quick Start is meant to jump start the biological cycling of a tank and is only needed for new tanks or potentially semi established tanks that have a spike in ammonia and nitrite levels which could be caused by adding more fish.  You can stop using this once your water chemistry has stabilized.  API Stress Zyme is very similar in function to the Quick Start and is generally chosen to improve water clarity or stabilize chemistry in more established tanks.    You don't need to use both simultaneously and would probably never see the difference compared to using just one.  On another note, I always add my bacteria after there is no chance there is any chlorine so they have a better chance of proliferating.  I would add either the Quick Start or the Stress Zyme the day after a water change, directly into the tank.

**Q: can i mix stress coat, stress zyme and tap water conditioner? if so what amount of each should i mix? doing this harm my fishes?**
A: Stress Coat and water conditioner is the same. ( stress Coat is water conditioner ). if you use both at the same time that you double it up. Maybe it is nothing will happening . But, it is not necessary to do that.

**Q: How long this product can be stored before it expires?  Also, would its effectiveness reduce during long time storage?**
A: As for length of time you can store, I use it weekly and it lasts for about four months or so. Does not seem to lose effectiveness in that time.

**Q: What is the expiration date on this Stress Zyme?  It seems very inexpensive.**
A: There is an expiration date on the bottle, however, these are live bacteria and once the bottle is open the shelf life is cut in half. Same as Seachems Pristine. Buy the size bottle for your tank. There is 250ml and 500 or 750ml, depending on the brand. My personal and professional advice is buy the smaller one 1st and see how much you go through, follow the instructions completely. They work well, keeps the glass cleaner longer. Also very important, make sure the aeriation is adequate and they say to change the filters 1st. If you have the $$ go for it. Best and least expensive and just as sufficient, is to change them half way before you normally change out your filters. API Stress zyme seems to keep its life span quite a while after opening. But trust me, you'll use it up way before it expires. Compared to the other similar products, this one seems to leave more of a brownish pile on the corners or underneath Ornaments, whis in turn will have to be vacuumed, netted or a baster for cooking depending on the size of your tank. 👍

## Customer Reviews

### ⭐⭐⭐⭐⭐ Clear water
*by G***O on February 4, 2026*

It works great. Keep my water crystal clear.

### ⭐⭐⭐⭐⭐ Amazing product. Really works.
*by A***6 on July 13, 2025*

I use this weekly, RELIGIOUSLY. I do not miss a dose. This is my tank today, having not touched the filter in 18 months. (Fluval FX6 filled with only biohome filter media and polishing sponges.) I’ve only changed out the live plants when needed (pothos houseplant clippings) and used the magnetic algae glass scraper when needed. It’s a 75 gallon tank. I8 MONTHS!!! I highly recommend this product. Zero odor, zero nastiness.

### ⭐⭐⭐⭐⭐ Great for my aquatic frogs
*by J***N on December 8, 2025*

I use this religiously with my African dwarf frogs! They are still kicking strong after 3 years so it must be working!

## Frequently Bought Together

- API STRESS ZYME Freshwater and Saltwater Aquarium Cleaning Solution 16-Ounce Bottle
- API STRESS COAT Aquarium Water Conditioner 16-Ounce Bottle
- API QUICK START Freshwater and Saltwater Aquarium Nitrifying Bacteria 16-Ounce Bottle

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*Product available on Desertcart Italy*
*Store origin: IT*
*Last updated: 2026-02-20*